Our papers, ordered by year.

Key

R Link to released and documented software package, where the paper describes a method with accompanying software.

R The results in papers are generated by analysis scripts that are separate from any associated software. It may not be as pretty, or unit tested, or well documented, but nonetheless, in an effort towards best reproducible research, we are trying to release the code supporting published results.

2023

1. Sharing GWAS summary statistics results in more citations Reales G, Wallace C.

   Communications Biology 2023 DOI
2. Accurate detection of shared genetic architecture from GWAS summary statistics in the small-sample context Willis T, Wallace C.

   bioRxiv 2023 DOI preprint
3. CoPheScan: phenome-wide association studies accounting for linkage disequilibrium Manipur I, Reales G, Sul J, Shin M, Longerich S, Cortes A, Wallace C.

   bioRxiv 2023
4. BBmix: a Bayesian beta-binomial mixture model for accurate genotyping from RNA-sequencing Vigorito E, Barton A, Pitzalis C, Lewis M, Wallace C.

   Bioinformatics 2023 DOI preprint

2022

1. Probabilistic classification of anti-SARS-CoV-2 antibody responses improves seroprevalence estimates. Castro Dopico X, Muschiol S, Grinberg N, Aleman S, Sheward D, Hanke L, Ahl M, Vikström L, Forsell M, Coquet J, McInerney G, Dillner J, Bogdanovic G, Murrell B, Albert J, Wallace C, Karlsson Hedestam G.

   Clinical & translational immunology 2022 DOI
2. A semi-supervised Bayesian mixture modelling approach for joint batch correction and classification Coleman S, Dopico X, Hedestam G, Kirk P, Wallace C.

   2022 DOI
3. Autoimmunity is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension Jones R, De Bie E, Groves E, Zalewska K, Swietlik E, Treacy C, Martin J, Polwarth G, Li W, Guo J, Baxendale H, Coleman S, Savinykh N, Coghlan J, Corris P, Howard L, Johnson M, Church C, Kiely D, Lawrie A, Lordan J, Mackenzie Ross R, Pepke Zaba J, Wilkins M, Wort S, Fiorillo E, Orrù V, Cucca F, Rhodes C, Gräf S, Morrell N, McKinney E, Wallace C, *Toshner M.

   American Journal of Respiratory and Critical Care Medicine 2022 DOI preprint
4. Combining evidence from Mendelian randomization and colocalization: Review and comparison of approaches Zuber V, Grinberg N, Gill D, Manipur I, Slob E, Patel A, Wallace C, Burgess S.

   The American Journal of Human Genetics 2022 DOI
5. Mendelian randomization Sanderson E, Glymour M, Holmes M, Kang H, Morrison J, Munafò M, Palmer T, Schooling C, Wallace C, Zhao Q, Davey Smith G.

   Nature Reviews Methods Primers 2022 DOI
6. fcfdr: an R package to leverage continuous and binary functional genomic data in GWAS Hutchinson A, Liley J, Wallace C.

   BMC Bioinformatics 2022 DOI
7. Bayesian clustering with uncertain data Nicholls K, Kirk P, Wallace C.

   2022 DOI
8. BBmix: a Bayesian Beta-Binomial mixture model for accurate genotyping from RNA-sequencing Vigorito E, Barton A, Pitzalis C, Lewis M, Wallace C.

   bioRxiv 2022 DOI preprint

2021

1. Multi-Tissue Transcriptome-Wide Association Studies Grinberg N, Wallace C.

   Genetic Epidemiology 2021 DOI preprint
2. Accurate Error Control in High-Dimensional Association Testing Using Conditional False Discovery Rates Liley J, Wallace C.

   Biometrical Journal 2021 DOI
3. Detection of quantitative trait loci from RNA-seq data with or without genotypes using BaseQTL Vigorito E, Lin W, Starr C, Kirk P, White S, Wallace C.

   Nat Comp Sci 2021 DOI preprint
4. Comparison of sparse biclustering algorithms for gene expression datasets Nicholls K, Wallace C.

   Briefings in Bioinformatics 2021 DOI
5. A more accurate method for colocalisation analysis allowing for multiple causal variants Wallace C.

   PLOS Genetics 2021 DOI
6. RapidoPGS: A rapid polygenic score calculator for summary GWAS data without a test dataset Reales G, Vigorito E, Kelemen M, Wallace C.

   Bioinformatics 2021 DOI
7. Seropositivity in blood donors and pregnant women during the first year of SARS-CoV-2 transmission in Stockholm, Sweden Castro Dopico X, Muschiol S, Christian M, Hanke L, Sheward D, Grinberg N, Rorbach J, Bogdanovic G, Mcinerney G, Allander T, Wallace C, Murrell B, Albert J, Karlsson Hedestam G.

   Journal of Internal Medicine 2021 DOI preprint
8. Detecting chromosomal interactions in Capture Hi-C data with CHiCAGO and companion tools Freire-Pritchett P, Ray-Jones H, Della Rosa M, Eijsbouts C, Orchard W, Wingett S, Wallace C, Cairns J, Spivakov M, Malysheva V.

   Nature Protocols 2021
9. EPISPOT: an epigenome-driven approach for detecting and interpreting hotspots in molecular QTL studies Ruffieux H, Fairfax B, Nassiri I, Vigorito E, Wallace C, Richardson S, Bottolo L.

   The American Journal of Human Genetics 2021
10. Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR Hutchinson A, Reales G, Willis T, Wallace C.

    PLOS Genetics 2021 DOI preprint
11. The flashfm approach for fine-mapping multiple quantitative traits Hernández N, Soenksen J, Newcombe P, Sandhu M, Barroso I, Wallace C, Asimit J.

    Nature Communications 2021 DOI preprint
12. ShaPRS: Leveraging shared genetic effects across traits or ancestries improves accuracy of polygenic scores Kelemen M, Vigorito E, Anderson C, Wallace C.

    medRxiv 2021 DOI preprint
13. fcfdr: an R package to leverage continuous and binary functional genomic data in GWAS Hutchinson A, Liley J, Wallace C.

    2021 DOI

2020

1. Resolving Mechanisms of Immune-Mediated Disease in Primary CD4 T Cells Bourges C, Groff A, Burren O, Gerhardinger C, Mattioli K, Hutchinson A, Hu T, Anand T, Epping M, Wallace C, Smith K, Rinn J, Lee J.

   EMBO Molecular Medicine 2020 DOI preprint
2. Genetic Feature Engineering Enables Characterisation of Shared Risk Factors in Immune-Mediated Diseases Burren O, Reales G, Wong L, Bowes J, Lee J, Barton A, Lyons P, Smith K, Thomson W, Kirk P, Wallace C.

   Genome Medicine 2020 DOI preprint
3. Fine-Mapping Genetic Associations Hutchinson A, Asimit J, Wallace C.

   Human Molecular Genetics 2020 DOI
4. Identification of Susceptibility Loci for Takayasu Arteritis through a Large Multi-Ancestral Genome-Wide Association Study Ortiz-Fernández L, Saruhan-Direskeneli G, Alibaz-Oner F, Kaymaz-Tahra S, Coit P, Kong X, Kiprianos A, Maughan R, Aydin S, Aksu K, Keser G, Kamali S, Inanc M, Springer J, Akar S, Onen F, Akkoc N, Khalidi N, Koening C, Karadag O, Kiraz S, Forbess L, Langford C, McAlear C, Ozbalkan Z, Yavuz S, Çetin G, Alpay-Kanitez N, Chung S, Ates A, Karaaslan Y, McKinnon-Maksimowicz K, Monach P, Ozer H, Seyahi E, Fresko I, Cefle A, Seo P, Warrington K, Ozturk M, Ytterberg S, Cobankara V, Onat A, Duzgun N, Bıcakcıgil M, Yentür S, Lally L, Manfredi A, Baldissera E, Erken E, Yazici A, Kısacık B, Kaşifoğlu T, Dalkilic E, Cuthbertson D, Pagnoux C, Sreih A, Reales G, Wallace C, Wren J, Cunninghame-Graham D, Vyse T, Sun Y, Chen H, Grayson P, Tombetti E, Jiang L, Mason J, Merkel P, Direskeneli H, Sawalha A.

   American Journal of Human Genetics 2020 DOI
5. Eliciting Priors and Relaxing the Single Causal Variant Assumption in Colocalisation Analyses Wallace C.

   PLOS Genetics 2020 DOI
6. Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters. Mitchelmore J, Grinberg N, Wallace C, Spivakov M.

   Nucleic acids research 2020 DOI PMC
7. Consensus clustering for Bayesian mixture models Coleman S, Kirk P, Wallace C.

   bioRxiv 2020 DOI preprint

2019

1. Eliciting Priors and Relaxing the Single Causal Variant Assumption in Colocalisation Analyses Wallace C.

   bioRxiv 2019 DOI preprint
2. Correcting the Coverage of Credible Sets in Bayesian Genetic Fine-Mapping Hutchinson A, Watson H, Wallace C.

   bioRxiv 2019 DOI preprint
3. Functional Effects of Variation in Transcription Factor Binding Highlight Long-Range Gene Regulation by Epromoters Mitchelmore J, Grinberg N, Wallace C, Spivakov M.

   bioRxiv 2019 DOI preprint
4. Fine Mapping Chromatin Contacts in Capture Hi-C Data. Eijsbouts C, Burren O, Newcombe P, Wallace C.

   BMC genomics 2019 DOI R R
5. Genome-Wide Association Study of Eosinophilic Granulomatosis with Polyangiitis Reveals Genomic Loci Stratified by ANCA Status Lyons P, Peters J, Alberici F, Liley J, Coulson R, Astle W, Baldini C, Bonatti F, Cid M, Elding H, Emmi G, Epplen J, Guillevin L, Jayne D, Jiang T, Gunnarsson I, Lamprecht P, Leslie S, Little M, Martorana D, Moosig F, Neumann T, Ohlsson S, Quickert S, Ramirez G, Rewerska B, Schett G, Sinico R, Szczeklik W, Tesar V, Vukcevic D, Akil M, Barratt J, Basu N, Butterworth A, Bruce I, Clarkson M, Conlon N, DasGupta B, Doulton T, Espígol-Frigolé G, Flossmann O, Gabrielli A, Gasior J, Gregorini G, Guida G, Hernández-Rodríguez J, Hruskova Z, Hudson A, Knight A, Lanyon P, Luqmani R, Magliano M, Manfredi A, Marguerie C, Maritati F, Marvisi C, McHugh N, Molloy E, Motyer A, Mukhtyar C, Padyukov L, Pesci A, Prieto-Gonzalez S, Ramentol-Sintas M, Reis P, Roccatello D, Rovere-Querini P, Salvarani C, Santarsia F, Solans-Laque R, Soranzo N, Taylor J, Wessels J, Zwerina J, Terrier B, Watts R, Vaglio A, Holle J, Wallace C, Smith K, The European Vasculitis Genetics Consortium .

   Nat. Commun. 2019 DOI preprint
6. Multivariate Genome-Wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy Nath A, Ritchie S, Grinberg N, Tang H, Huang Q, Teo S, Ahola-Olli A, Würtz P, Havulinna A, Santalahti K, Pitkänen N, Lehtimäki T, Kähönen M, Lyytikäinen L, Raitoharju E, Seppälä I, Sarin A, Ripatti S, Palotie A, Perola M, Viikari J, Jalkanen S, Maksimow M, Salmi M, Wallace C, Raitakari O, Salomaa V, Abraham G, Kettunen J, Inouye M.

   Am. J. Hum. Genet. 2019 DOI
7. Stochastic Search and Joint Fine-Mapping Increases Accuracy and Identifies Previously Unreported Associations in Immune-Mediated Diseases Asimit J, Rainbow D, Fortune M, Grinberg N, Wicker L, Wallace C.

   Nat. Commun. 2019 DOI PMC

2018

1. The Chromosome 6q22.33 Region Is Associated with Age at Diagnosis of Type 1 Diabetes and Disease Risk in Those Diagnosed under 5 Years of Age Inshaw J, Walker N, Wallace C, Bottolo L, Todd J.

   Diabetologia 2018 DOI
2. DNA Methylation Oscillation Defines Classes of Enhancers Libertini E, Hamoudi R, Heath S, Lancashire L, Garcia A, Grassi L, Downes K, Ouwehand W, Javierre B, Cairns J, Wingett S, Paul D, Gut M, Gut I, Martens J, Ivliev A, Stunnenberg H, Frontini M, Spivakov M, Fraser P, Cutler A, Wallace C, Beck S.

   bioRxiv 2018 DOI preprint
3. Accurate Error Control in High Dimensional Association Testing Using Conditional False Discovery Rates Liley J, Wallace C.

   bioRxiv 2018 DOI preprint R R
4. Improved Consistency in Estimates of Conditional False Discovery Rates Increases Power Relative to Both Existing Methods and Parametric Estimators Liley J, Wallace C.

   bioRxiv 2018 DOI preprint R R
5. Fine Mapping Chromatin Contacts in Capture Hi-C Data Eijsbouts C, Burren O, Newcombe P, Wallace C.

   bioRxiv 2018
6. Accurate Error Control in High Dimensional Association Testing Using Conditional False Discovery Rates Liley J, Wallace C.

   2018 DOI
7. Promoter Interactome of Human Embryonic Stem Cell-Derived Cardiomyocytes Connects GWAS Regions to Cardiac Gene Networks Choy M, Javierre B, Williams S, Baross S, Liu Y, Wingett S, Akbarov A, Wallace C, Freire-Pritchett P, Rugg-Gunn P, Spivakov M, Fraser P, Keavney B.

   Nat. Commun. 2018 DOI
8. simGWAS: A Fast Method for Simulation of Large Scale Case-Control GWAS Summary Statistics Fortune M, Wallace C.

   Bioinformatics 2018 DOI preprint R R

2017

1. Chromosome Contacts in Activated T Cells Identify Autoimmune Disease Candidate Genes Burren O, Rubio García A, Javierre B, Rainbow D, Cairns J, Cooper N, Lambourne J, Schofield E, Castro Dopico X, Ferreira R, Coulson R, Burden F, Rowlston S, Downes K, Wingett S, Frontini M, Ouwehand W, Fraser P, Spivakov M, Todd J, Wicker L, Cutler A, Wallace C.

   Genome Biology 2017 DOI PMC R
2. Cells with Treg-Specific FOXP3 Demethylation but Low CD25 Are Prevalent in Autoimmunity Ferreira R, Simons H, Thompson W, Rainbow D, Yang X, Cutler A, Oliveira J, Castro Dopico X, Smyth D, Savinykh N, Mashar M, Vyse T, Dunger D, Baxendale H, Chandra A, Wallace C, Todd J, Wicker L, Pekalski M.

   Journal of autoimmunity 2017 DOI PMC
3. Neonatal and Adult Recent Thymic Emigrants Produce IL-8 and Express Complement Receptors CR1 and CR2 Pekalski M, García A, Ferreira R, Rainbow D, Smyth D, Mashar M, Brady J, Savinykh N, Dopico X, Mahmood S, Duley S, Stevens H, Walker N, Cutler A, Waldron-Lynch F, Dunger D, Shannon-Lowe C, Coles A, Jones J, Wallace C, Todd J, Wicker L.

   JCI insight 2017 DOI PMC
4. A Method for Identifying Genetic Heterogeneity within Phenotypically-Defined Disease Subgroups Liley J, Todd J, Wallace C.

   Nat Genet 2017 DOI PMC R
5. Chromosome Contacts in Activated T Cells Identify Autoimmune Disease Candidate Genes Burren O, Garcia A, Javierre B, Rainbow D, Cairns J, Cooper N, Lambourne J, Schofield E, Dopico X, Ferreira R, Coulson R, Burden F, Rowlston S, Downes K, Wingett S, Frontini M, Ouwehand W, Fraser P, Spivakov M, Todd J, Wicker L, Cutler A, Wallace C.

   Genome Biol. 2017 DOI
6. Type 1 Diabetes Genome-Wide Association Analysis with Imputation Identifies Five New Risk Regions Cooper N, Wallace C, Burren O, Cutler A, Walker N, Todd J.

   2017 DOI
7. Validation of the AUDIT-C in Adults Seeking Help with Their Drinking Online Khadjesari Z, White I, McCambridge J, Marston L, Wallace P, Godfrey C, Murray E.

   Addict. Sci. Clin. Pract. 2017 DOI PMC
8. A Method for Identifying Genetic Heterogeneity within Phenotypically Defined Disease Subgroups Liley J, Todd J, Wallace C.

   Nat. Genet. 2017 DOI
9. Transcriptional Risk Scores Link GWAS to eQTLs and Predict Complications in Crohn’s Disease Marigorta U, Denson L, Hyams J, Mondal K, Prince J, Walters T, Griffiths A, Noe J, Crandall W, Rosh J, Mack D, Kellermayer R, Heyman M, Baker S, Stephens M, Baldassano R, Markowitz J, Kim M, Dubinsky M, Cho J, Aronow B, Kugathasan S, Gibson G.

   Nature Genetics 2017 DOI
10. A Rare IL2RA Haplotype Identifies SNP Rs61839660 as Causal for Autoimmunity Rainbow D, Pekalski M, Cutler A, Burren O, Walker N, Todd J, Wallace C, Wicker L.

    2017 DOI

2016

1. Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial Todd, John A. AND Evangelou, Marina AND Cutler, Antony J. AND Pekalski, Marcin L. AND Walker, Neil M. AND Stevens, Helen E. AND Porter, Linsey AND Smyth, Deborah J. AND Rainbow, Daniel B. AND Ferreira, Ricardo C. AND Esposito, Laura AND Hunter, Kara M. D. AND Loudon, Kevin AND Irons, Kathryn AND Yang, Jennie H. AND Bell, Charles J. M. AND Schuilenburg, Helen AND Heywood, James AND Challis, Ben AND Neupane, Sankalpa AND Clarke, Pamela AND Coleman, Gillian AND Dawson, Sarah AND Goymer, Donna AND Anselmiova, Katerina AND Kennet, Jane AND Brown, Judy AND Caddy, Sarah L. AND Lu, Jia AND Greatorex, Jane AND Goodfellow, Ian AND C Wallace AND Tree, Tim I. AND Evans, Mark AND Mander, Adrian P. AND Bond, Simon AND Wicker, Linda S. AND Waldron-Lynch, Frank .

   PLOS Medicine 2016 DOI
2. A Genetic Test for Differential Causative Pathology in Disease Subgroups Liley J, Todd J, Wallace C.

   2016 DOI
3. Lineage-Specific Genome Architecture Links Enhancers and Non-Coding Disease Variants to Target Gene Promoters Javierre B, Burren O, Wilder S, Kreuzhuber R, Hill S, Sewitz S, Cairns J, Wingett S, Várnai C, Thiecke M, Burden F, Farrow S, Cutler A, Rehnström K, Downes K, Grassi L, Kostadima M, Freire-Pritchett P, Wang F, BLUEPRINT Consortium , Stunnenberg H, Todd J, Zerbino D, Stegle O, Ouwehand W, Frontini M, Wallace C, Spivakov M, Fraser P.

   Cell 2016 DOI PMC R

2015

1. Widespread Seasonal Gene Expression Reveals Annual Differences in Human Immunity and Physiology. Castro Dopico X, Evangelou M, Ferreira R, Guo H, Pekalski M, Smyth D, Ziegler A, Bonifacio E, Wallace C, *Todd J.

   Nat Commun 2015 DOI PMC
2. Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-Standing Type 1 Diabetes Yang J, Cutler A, Ferreira R, Reading J, Cooper N, Wallace C, Clarke P, Smyth D, Boyce C, Gao G, Todd J, Wicker L, Tree T.

   Diabetes 2015 DOI PMC
3. Statistical Colocalization of Genetic Risk Variants for Related Autoimmune Diseases in the Context of Common Controls. Fortune M, Guo H, Burren O, Schofield E, Walker N, Ban M, Sawcer S, Bowes J, Worthington J, Barton A, Eyre S, Todd J, Wallace C.

   Nat Genet 2015 DOI PMC R
4. Corrigendum: Dense Genotyping of Immune-Related Susceptibility Loci Reveals New Insights into the Genetics of Psoriatic Arthritis Bowes J, Budu-Aggrey A, Huffmeier U, Uebe S, Steel K, Hebert H, Wallace C, Massey J, Bruce I, Bluett J, Feletar M, Morgan A, Marzo-Ortega H, Donohoe G, Morris D, Helliwell P, Ryan A, Kane D, Warren R, Korendowych E, Alenius G, Giardina E, Packham J, McManus R, FitzGerald O, McHugh N, Brown M, Ho P, Behrens F, Burkhardt H, Reis A, Barton A.

   Nat. Commun. 2015 DOI
5. Widespread Seasonal Gene Expression Reveals Annual Differences in Human Immunity and Physiology Dopico X, Evangelou M, Ferreira R, Guo H, Pekalski M, Smyth D, Cooper N, Burren O, Fulford A, Hennig B, Prentice A, Ziegler A, Bonifacio E, Wallace C, Todd J.

   Nat. Commun. 2015 DOI PMC
6. Corrigendum: Statistical Colocalization of Genetic Risk Variants for Related Autoimmune Diseases in the Context of Common Controls Fortune M, Guo H, Burren O, Schofield E, Walker N, Ban M, Sawcer S, Bowes J, Worthington J, Barton A, Eyre S, Todd J, Wallace C.

   Nat. Genet. 2015 DOI
7. Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping Wallace C, Cutler A, Pontikos N, Pekalski M, Burren O, Cooper J, Garcia A, Ferreira R, Guo H, Walker N, Smyth D, Rich S, Onengut-Gumuscu S, Sawcer S, Ban M, Richardson S, Todd J, Wicker L.

   PLoS Genet. 2015 DOI PMC R
8. Dense Genotyping of Immune-Related Susceptibility Loci Reveals New Insights into the Genetics of Psoriatic Arthritis. Bowes J, Budu-Aggrey A, Huffmeier U, Uebe S, Steel K, Hebert H, Wallace C, Massey J, Bruce I, Bluett J, Feletar M, Morgan A, Marzo-Ortega H, Donohoe G, Morris D, Helliwell P, Ryan A, Kane D, Warren R, Korendowych E, Alenius G, Giardina E, Packham J, McManus R, FitzGerald O, McHugh N, Brown M, Ho P, Behrens F, Burkhardt H, Reis A, Barton A.

   Nat Commun 2015 DOI PMC R
9. Integration of Disease Association and eQTL Data Using a Bayesian Colocalisation Approach Highlights Six Candidate Causal Genes in Immune-Mediated Diseases. Guo H, Fortune M, Burren O, Schofield E, Todd J, Wallace C.

   Hum Mol Genet 2015 DOI PMC
10. Capture Hi-C Reveals Novel Candidate Genes and Complex Long-Range Interactions with Related Autoimmune Risk Loci Martin P, McGovern A, Orozco G, Duffus K, Yarwood A, Schoenfelder S, Cooper N, Barton A, Wallace C, Fraser P, Worthington J, Eyre S.

    Nat. Commun. 2015 DOI PMC R
11. Fine Mapping of Type 1 Diabetes Susceptibility Loci and Evidence for Colocalization of Causal Variants with Lymphoid Gene Enhancers. Onengut-Gumuscu S, Chen W, Burren O, Cooper N, Quinlan A, Mychaleckyj J, Farber E, Bonnie J, Szpak M, Schofield E, Achuthan P, Guo H, Fortune M, Stevens H, Walker N, Ward L, Kundaje A, Kellis M, Daly M, Barrett J, Cooper J, Deloukas P, Type 1 Diabetes Genetics Consortium , Todd J, *Wallace C, *Concannon P, *Rich S.

    Nat Genet 2015 DOI PMC R
12. IL-21 Production by CD4^+ Effector T Cells and Frequency of Circulating Follicular Helper T Cells Are Increased in Type 1 Diabetes Patients Ferreira R, Simons H, Thompson W, Cutler A, Dopico X, Smyth D, Mashar M, Schuilenburg H, Walker N, Dunger D, Wallace C, Todd J, Wicker L, Pekalski M.

    Diabetologia 2015 DOI PMC
13. Epigenetic Analysis of Regulatory T Cells Using Multiplex Bisulfite Sequencing Rainbow D, Yang X, Burren O, Pekalski M, Smyth D, Klarqvist M, Penkett C, Brugger K, Martin H, Todd J, Wallace C, Wicker L.

    European journal of immunology 2015 DOI PMC
14. A Pleiotropy-Informed Bayesian False Discovery Rate Adapted to a Shared Control Design Finds New Disease Associations From GWAS Summary Statistics Liley J, Wallace C.

    PLoS Genet 2015 DOI PMC R

2014

1. Multi-Parametric Flow Cytometric and Genetic Investigation of the Peripheral B Cell Compartment in Human Type 1 Diabetes. Thompson W, Pekalski M, Simons H, Smyth D, Castro-Dopico X, Guo H, Guy C, Dunger D, Arif S, Peakman M, Wallace C, Wicker L, Todd J, Ferreira R.

   Clin Exp Immunol 2014 DOI PMC
2. A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically At-Risk of Type 1 Diabetes. Ferreira R, Guo H, Coulson R, Smyth D, Pekalski M, Burren O, Cutler A, Doecke J, Flint S, McKinney E, Lyons P, Smith K, Achenbach P, Beyerlein A, Dunger D, Wicker L, Todd J , *Bonifacio E , *Wallace C, *Ziegler G .

   Diabetes 2014 DOI PMC
3. Plasma Concentrations of Soluble IL-2 Receptor (CD25) Are Increased in Type 1 Diabetes and Associated with Reduced C-Peptide Levels in Young Patients. Downes K, Marcovecchio M, Clarke P, Cooper J, Ferreira R, Howson J, Jolley J, Nutland S, Stevens H, Walker N, Wallace C, Dunger D, Todd J.

   Diabetologia 2014 DOI PMC
4. A Genome-Wide Assessment of the Role of Untagged Copy Number Variants in Type 1 Diabetes. Zanda M, Onengut-Gumuscu S, Walker N, Shtir C, Gallo D, Wallace C, Smyth D, Todd J, Hurles M, Plagnol V, Rich S.

   PLoS Genet 2014 DOI PMC
5. Plasma Concentrations of Soluble IL-2 Receptor α (CD25) Are Increased in Type 1 Diabetes and Associated with Reduced C-Peptide Levels in Young Patients Downes K, Marcovecchio M, Clarke P, Cooper J, Ferreira R, Howson J, Jolley J, Nutland S, Stevens H, Walker N, Wallace C, Dunger D, Todd J.

   Diabetologia 2014 DOI
6. A Hybrid qPCR/SNP Array Approach Allows Cost Efficient Assessment of KIR Gene Copy Numbers in Large Samples Pontikos N, Smyth D, Schuilenburg H, Howson J, Walker N, Burren O, Guo H, Onengut-Gumuscu S, Chen W, Concannon P, Rich S, Jayaraman J, Jiang W, Traherne J, Trowsdale J, Todd J, Wallace C.

   BMC Genomics 2014 DOI PMC
7. VSEAMS: A Pipeline for Variant Set Enrichment Analysis Using Summary GWAS Data Identifies IKZF3, BATF and ESRRA as Key Transcription Factors in Type 1 Diabetes. Burren O, Guo H, Wallace C.

   Bioinformatics 2014 DOI PMC R
8. A Method for Gene-Based Pathway Analysis Using Genomewide Association Study Summary Statistics Reveals Nine New Type 1 Diabetes Associations Evangelou M, Smyth D, Fortune M, Burren O, Walker N, Guo H, Onengut-Gumuscu S, Chen W, Concannon P, Rich S, Todd J, Wallace C.

   Genet. Epidemiol. 2014 DOI PMC
9. Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics. Giambartolomei C, Vukcevic D, Schadt E, Franke L, Hingorani A, Wallace C, Plagnol V.

   PLoS Genet 2014 DOI PMC R

2013

1. Dense Genotyping of Immune-Related Disease Regions Identifies 14 New Susceptibility Loci for Juvenile Idiopathic Arthritis Hinks A, Cobb J, Marion M, Prahalad S, Sudman M, Bowes J, Martin P, Comeau M, Sajuthi S, Andrews R, Brown M, Chen W, Concannon P, Deloukas P, Edkins S, Eyre S, Gaffney P, Guthery S, Guthridge J, Hunt S, James J, Keddache M, Moser K, Nigrovic P, Onengut-Gumuscu S, Onslow M, Rosé C, Rich S, Steel K, Wakeland E, Wallace C, Wedderburn L, Woo P, Boston Children’s J I A Registry , British Society of Paediatric , Group A, Childhood Arthritis Prospective Study (C A P S) , Childhood Arthritis Response to Medication Study (C H A R M S) , German Society For Pediatric Rheumatology (G K J R) , J I A Gene Expression Study , N I A M S J I A Genetic Registry , T R E A T Study , United Kingdom Juvenile Idiopathic Arthritis Genetics Consortium (U K J I A G C) , Bohnsack J, Haas J, Glass D, Langefeld C, Thomson W, Thompson S.

   Nature Publishing Group 2013 DOI PMC
2. Postthymic Expansion in Human CD4 Naive T Cells Defined by Expression of Functional High-Affinity IL-2 Receptors. Pekalski M, Ferreira R, Coulson R, Cutler A, Guo H, Smyth D, Downes K, Dendrou C, Castro Dopico X, Esposito L, Coleman G, Stevens H, Nutland S, Walker N, Guy C, Dunger D, Wallace C, Tree T, Todd J, Wicker L.

   J Immunol 2013 DOI PMC
3. Statistical Testing of Shared Genetic Control for Potentially Related Traits. Wallace C.

   Genet Epidemiol 2013 DOI PMC R

2012

1. Comparative Analysis of Genome-Wide Association Studies Signals for Lipids, Diabetes, and Coronary Heart Disease: Cardiovascular Biomarker Genetics Collaboration. Angelakopoulou A, Shah T, Sofat R, Shah S, Berry D, Cooper J, Palmen J, Tzoulaki I, Wong A, Jefferis B, Maniatis N, Drenos F, Gigante B, Hardy R, Laxton R, Leander K, Motterle A, Simpson I, Smeeth L, Thomson A, Verzilli C, Kuh D, Ireland H, Deanfield J, Caulfield M, Wallace C, Samani N, Munroe P, Lathrop M, Fowkes F, Marmot M, Whincup P, Whittaker J, de Faire U, Kivimaki M, Kumari M, Hypponen E, Power C, Humphries S, Talmud P, Price J, Morris R, Ye S, Casas J, Hingorani A.

   Eur Heart J 2012 DOI PMC
2. Genome-Wide Association Analyses Identify 13 New Susceptibility Loci for Generalized Vitiligo Jin Y, Birlea S, Fain P, Ferrara T, Ben S, Riccardi S, Cole J, Gowan K, Holland P, Bennett D, Luiten R, Wolkerstorfer A, van der Veen J, Hartmann A, Eichner S, Schuler G, van Geel N, Lambert J, Kemp E, Gawkrodger D, Weetman A, Taïeb A, Jouary T, Ezzedine K, Wallace M, McCormack W, Picardo M, Leone G, Overbeck A, Silverberg N, Spritz R.

   Nat. Genet. 2012 DOI PMC
3. Extra-Binomial Variation Approach for Analysis of Pooled DNA Sequencing Data. Yang X, Todd J, Clayton D, Wallace C.

   Bioinformatics 2012 DOI PMC
4. Seven Newly Identified Loci for Autoimmune Thyroid Disease. Cooper J, Simmonds M, Walker N, Burren O, Brand O, Guo H, Wallace C, Stevens H, Coleman G, Wellcome Trust Case Control Consortium , Franklyn J, Todd J, Gough S.

   Hum Mol Genet 2012 DOI PMC
5. Long-Range DNA Looping and Gene Expression Analyses Identify DEXI as an Autoimmune Disease Candidate Gene. Davison, L , Wallace C, Cooper J, Cope N, Wilson N, Smyth D, Howson J, Saleh N, Al-Jeffery A, Angus K, Stevens H, Nutland S, Duley S, Coulson R, Walker N, Burren O, Rice C, Cambien F, Zeller T, Munzel T, Lackner K, Blankenberg S, Cardiogenics Consortium , Fraser P, Gottgens B, Todd J.

   Hum Mol Genet 2012 DOI PMC
6. Statistical Colocalization of Monocyte Gene Expression and Genetic Risk Variants for Type 1 Diabetes. Wallace C, Rotival M, Cooper J, Rice C, Yang J, McNeill M, Smyth D, Niblett D, Cambien F, Cardiogenics Consortium , Tiret L, Todd J, Clayton D, Blankenberg S.

   Hum Mol Genet 2012 DOI PMC

2011

1. Inherited Variation in Vitamin D Genes Is Associated with Predisposition to Autoimmune Disease Type 1 Diabetes. Cooper J, Smyth D, Walker N, Stevens H, Burren O, Wallace C, Greissl C, Ramos-Lopez E, HyppÃnen E, Dunger D, Spector T, Ouwehand W, Wang T, Badenhoop K, Todd J.

   Diabetes 2011 DOI PMC
2. Blood Pressure Loci Identified with a Gene-Centric Array Johnson T, Gaunt T, Newhouse S, Padmanabhan S, Tomaszewski M, Kumari M, Morris R, Tzoulaki I, O’Brien E, Poulter N, Sever P, Shields D, Thom S, Wannamethee S, Whincup P, Brown M, Connell J, Dobson R, Howard P, Mein C, Onipinla A, Shaw-Hawkins S, Zhang Y, Smith G, Day I, Lawlor D, Goodall A, Fowkes F, Abecasis G, Elliott P, Gateva V, Braund P, Burton P, Nelson C, Tobin M, Van Der Harst P, Glorioso N, Neuvrith H, Salvi E, Staessen J, Stucchi A, Devos N, Jeunemaitre X, Plouin P, Tichet J, Juhanson P, Org E, Putku M, Sauber S, Veldre G, Viigimaa M, Levinsson A, Rosengren A, Thelle D, Hastie C, Hedner T, Lee W, Melander O, Wahlstrand B, Hardy R, Wong A, Cooper J, Palmen J, Chen L, Stewart A, Wells G, Westra H, Wolfs M, Clarke R, Franzosi M, Goel A, Hamsten A, Lathrop M, Peden J, Seedorf U, Watkins H, Ouwehand W, Sambrook J, Stephens J, Casas J, Drenos F, Holmes M, Kivimaki M, Shah S, Shah T, Talmud P, Whittaker J, Wallace C, Delles C, Laan M, Kuh D, Humphries S, Nyberg F, Cusi D, Roberts R, Newton-Cheh C, Franke L, Stanton A, Dominiczak A, Farrall M, Hingorani A, Samani N, Caulfield M, Munroe P.

   American Journal of Human Genetics 2011 PMC
3. Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk. for Blood Pressure Genome-Wide Association Studies I, Ehret G, Munroe P, Rice K, Bochud M, Johnson A, Chasman D, Smith A, Tobin M, Verwoert G, Hwang S, Pihur V, Vollenweider P, O’Reilly P, Amin N, Bragg-Gresham J, Teumer A, Glazer N, Launer L, Zhao J, Aulchenko Y, Heath S, SÃ\textmuber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks A, Jackson A, Peden J, Tanaka T, Wild S, Rudan I, Igl W, Milaneschi Y, Parker A, Fava C, Chambers J, Fox E, Kumari M, Go M, van der Harst P, Kao W, SjÃ\textparagraphgren M, Vinay D, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup P, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen K, LehtimÃ\textcurrencyki T, Matullo G, Wu Y, Gaunt T, Onland-Moret N, Cooper M, Platou C, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund P, Kuznetsova T, Uiterwaal C, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer N, consortium C, Consortium C, Consortium K, consortium E, consortium C, Aspelund T, Garcia M, Chang Y, O’Connell J, Steinle N, Grobbee D, Arking D, Kardia S, Morrison A, Hernandez D, Najjar S, McArdle W, Hadley D, Brown M, Connell J, Hingorani A, Day I, Lawlor D, Beilby J, Lawrence R, Clarke R, Hopewell J, Ongen H, Dreisbach A, Li Y, Young J, Bis J, KÃ\textcurrencyhÃ\textparagraphnen M, Viikari J, Adair L, Lee N, Chen M, Olden M, Pattaro C, Bolton J, KÃ\textparagraphttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling T, Islam M, Jafar T, Erdmann J, Kulkarni S, Bornstein S, GrÃ\textcurrencyssler J, Groop L, Voight B, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw K, Weder A, Hunt S, Sun Y, Bergman R, Collins F, Bonnycastle L, Scott L, Stringham H, Peltonen L, Perola M, Vartiainen E, Brand S, Staessen J, Wang T, Burton P, Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman K, Rudock M, Heckbert S, Smith N, Wiggins K, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld C, Rosengren A, Thelle D, Corsi A, Singleton A, Forrester T, Hilton G, McKenzie C, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann H, Cho Y, Kim H, Lee J, Scott J, Sehmi J, Zhang W, Hedblad B, Nilsson P, Smith G, Wong A, Narisu N, StančÃ\textexclamdownkovÃ\textexclamdown A, Raffel L, Yao J, Kathiresan S, O’Donnell C, Schwartz S, Ikram M, Longstreth W, Mosley T, Seshadri S, Shrine N, Wain L, Morken M, Swift A, Laitinen J, Prokopenko I, Zitting P, Cooper J, Humphries S, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker S, van Gilst W, Janipalli C, Mani K, Yajnik C, Hofman A, Mattace-Raso F, Oostra B, Demirkan A, Isaacs A, Rivadeneira F, Lakatta E, Orru M, Scuteri A, Ala-Korpela M, Kangas A, LyytikÃ\textcurrencyinen L, Soininen P, Tukiainen T, WÃ\frac14rtz P, Ong R, DÃ\textparagraphrr M, Kroemer H, VÃ\textparagraphlker U, VÃ\textparagraphlzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector T, Zhai G, Meschia J, Nalls M, Sharma P, Terzic J, Kumar M, Denniff M, Zukowska-Szczechowska E, Wagenknecht L, Fowkes F, Charchar F, Schwarz P, Hayward C, Guo X, Rotimi C, Bots M, Brand E, Samani N, Polasek O, Talmud P, Nyberg F, Kuh D, Laan M, Hveem K, Palmer L, van der Schouw Y, Casas J, Mohlke K, Vineis P, Raitakari O, Ganesh S, Wong T, Tai E, Cooper R, Laakso M, Rao D, Harris T, Morris R, Dominiczak A, Kivimaki M, Marmot M, Miki T, Saleheen D, Chandak G, Coresh J, Navis G, Salomaa V, Han B, Zhu X, Kooner J, Melander O, Ridker P, Bandinelli S, Gyllensten U, Wright A, Wilson J, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller P, Elosua R, Soranzo N, Sijbrands E, Altshuler D, Loos R, Shuldiner A, Gieger C, Meneton P, Uitterlinden A, Wareham N, Gudnason V, Rotter J, Rettig R, Uda M, Strachan D, Witteman J, Hartikainen A, Beckmann J, Boerwinkle E, Vasan R, Boehnke M, Larson M, JÃ\textcurrencyrvelin M, Psaty B, Abecasis G, Chakravarti A, Elliott P, van Duijn C, Newton-Cheh C, Levy D, Caulfield M, Johnson T, Tang H, Knowles J, Hlatky M, Fortmann S, Assimes T, Quertermous T, Go A, Iribarren C, Absher D, Risch N, Myers R, Sidney S, Ziegler A, Schillert A, Bickel C, Sinning C, Rupprecht H, Lackner K, Wild P, Schnabel R, Blankenberg S, Zeller T, MÃ\frac14nzel T, Perret C, Cambien F, Tiret L, Nicaud V, Proust C, Dehghan A, Hofman A, Uitterlinden A, van Duijn C, Levy D, Whitteman J, Cupples L, Demissie-Banjaw S, Ramachandran V, Smith A, Gudnason V, Boerwinkle E, Folsom A, Morrison A, Psaty B, Chen I, Rotter J, Bis J, Volcik K, Rice K, Taylor K, Marciante K, Smith N, Glazer N, Heckbert S, Harris T, Lumley T, Kong A, Thorleifsson G, Thorgeirsson G, Holm H, Gulcher J, Stefansson K, Andersen K, Gretarsdottir S, Thorsteinsdottir U, Preuss M, Schreiber S, Meitinger T, KÃ\textparagraphnig I, Lieb W, Hengstenberg C, Schunkert H, Erdmann J, Fischer M, Grosshennig A, Medack A, Stark K, Linsel-Nitschke P, Bruse P, Aherrahrou Z, Peters A, Loley C, Willenborg C, Nahrstedt J, Freyer J, Gulde S, Doering A, Meisinger C, Wichmann H, Klopp N, Illig T, Meinitzer A, Tomaschitz A, Halperin E, Dobnig H, Scharnagl H, Kleber M, Laaksonen R, Pilz S, Grammer T, Stojakovic T, Renner W, MÃ\textcurrencyrz W, BÃ\textparagraphhm B, Winkelmann B, Winkler K, Hoffmann M, O’Donnell C, Voight B, Altshuler D, Siscovick D, Musunuru K, Peltonen L, Barbalic M, Melander O, Elosua R, Kathiresan S, Schwartz S, Salomaa V, Guiducci C, Burtt N, Gabriel S, Stewart A, Wells G, Chen L, Jarinova O, Roberts R, McPherson R, Dandona S, Pichard A, Rader D, Devaney J, Lindsay J, Kent K, Qu L, Satler L, Burnett M, Li M, Reilly M, Wilensky R, Waksman R, Epstein S, Matthai W, Knouff C, Waterworth D, Hakonarson H, Walker M, Mooser V, Hall A, Balmforth A, Wright B, Nelson C, Thompson J, Samani N, Braund P, Ball S, Smith N, Felix J, Morrison A, Demissie S, Glazer N, Loehr L, Cupples L, Dehghan A, Lumley T, Rosamond W, Lieb W, Rivadeneira F, Bis J, Folsom A, Benjamin E, Aulchenko Y, Haritunians T, Couper D, Murabito J, Wang Y, Stricker B, Gottdiener J, Chang P, Wang T, Rice K, Hofman A, Heckbert S, Fox E, O’Donnell C, Uitterlinden A, Rotter J, Willerson J, Levy D, van Duijn C, Psaty B, Witteman J, Boerwinkle E, Vasan R, KÃ\textparagraphttgen A, Pattaro C, BÃ\textparagraphger C, Fuchsberger C, Olden M, Glazer N, Parsa A, Gao X, Yang Q, Smith A, O’Connell J, Li M, Schmidt H, Tanaka T, Isaacs A, Ketkar S, Hwang S, Johnson A, Dehghan A, Teumer A, ParÃ\textcopyright G, Atkinson E, Zeller T, Lohman K, Cornelis M, Probst-Hensch N, Kronenberg F, TÃ\textparagraphnjes A, Hayward C, Aspelund T, Eiriksdottir G, Launer L, Harris T, Rampersaud E, Mitchell B, Arking D, Boerwinkle E, Struchalin M, Cavalieri M, Singleton A, Giallauria F, Metter J, de Boer J, Haritunians T, Lumley T, Siscovick D, Psaty B, Zillikens M, Oostra B, Feitosa M, Province M, de Andrade M, Turner S, Schillert A, Ziegler A, Wild P, Schnabel R, Wilde S, Munzel T, Leak T, Illig T, Klopp N, Meisinger C, Wichmann H, Koenig W, Zgaga L, Zemunik T, Kolcic I, Minelli C, Hu F, Johansson A, Igl W, Zaboli G, Wild S, Wright A, Campbell H, Ellinghaus D, Schreiber S, Aulchenko Y, Felix J, Rivadeneira F, Uitterlinden A, Hofman A, Imboden M, Nitsch D, BrandstÃ\textcurrencytter A, Kollerits B, Kedenko L, MÃ\textcurrencygi R, Stumvoll M, Kovacs P, Boban M, Campbell S, Endlich K, VÃ\textparagraphlzke H, Kroemer H, Nauck M, VÃ\textparagraphlker U, Polasek O, Vitart V, Badola S, Parker A, Ridker P, Kardia S, Blankenberg S, Liu Y, Curhan G, Franke A, Rochat T, Paulweber B, Prokopenko I, Wang W, Gudnason V, Shuldiner A, Coresh J, Schmidt R, Ferrucci L, Shlipak M, van Duijn C, Borecki I, KrÃ\textcurrencymer B, Rudan I, Gyllensten U, Wilson J, Witteman J, Pramstaller P, Rettig R, Hastie N, Chasman D, Kao W, Heid I, Fox C, Vasan R, Glazer N, Felix J, Lieb W, Wild P, Felix S, Watzinger N, Larson M, Smith N, Dehghan A, Grosshennig A, Schillert A, Teumer A, Schmidt R, Kathiresan S, Lumley T, Aulchenko Y, KÃ\textparagraphnig I, Zeller T, Homuth G, Struchalin M, Aragam J, Bis J, Rivadeneira F, Erdmann J, Schnabel R, DÃ\textparagraphrr M, Zweiker R, Lind L, Rodeheffer R, Greiser K, Levy D, Haritunians T, Deckers J, Stritzke J, Lackner K, VÃ\textparagraphlker U, Ingelsson E, Kullo I, Haerting J, O’Donnell C, Heckbert S, Stricker B, Ziegler A, Reffelmann T, Redfield M, Werdan K, Mitchell G, Rice K, Arnett D, Hofman A, Gottdiener J, Uitterlinden A, Meitinger T, Blettner M, Friedrich N, Wang T, Psaty B, van Duijn C, Wichmann H, Munzel T, Kroemer H, Benjamin E, Rotter J, Witteman J, Schunkert H, Schmidt H, Valzke H, Blankenberg S, Chambers J, Zhang W, Lord G, van der Harst P, Lawlor D, Sehmi J, Gale D, Wass M, Ahmadi K, Bakker S, Beckmann J, Bilo H, Bochud M, Brown M, Caulfield M, Connell J, Cook H, Cotlarciuc I, Smith G, de Silva R, Deng G, Devuyst O, Dikkeschei L, Dimkovic N, Dockrell M, Dominiczak A, Ebrahim S, Eggermann T, Farrall M, Ferrucci L, Floege J, Forouhi N, Gansevoort R, Han X, Hedblad B, van der Heide J, Hepkema B, Hernandez-Fuentes M, Hypponen E, Johnson T, de Jong P, Kleefstra N, Lagou V, Lapsley M, Li Y, Loos R, Luan J, Luttropp K, MarÃ\textcopyrightchal C, Melander O, Munroe P, Nordfors L, Parsa A, Peltonen L, Penninx B, Perucha E, Pouta A, Prokopenko I, Roderick P, Ruokonen A, Samani N, Sanna S, Schalling M, Schlessinger D, Schlieper G, Seelen M, Shuldiner A, SjÃ\textparagraphgren M, Smit J, Snieder H, Soranzo N, Spector T, Stenvinkel P, Sternberg M, Swaminathan R, Tanaka T, Ubink-Veltmaat L, Uda M, Vollenweider P, Wallace C, Waterworth D, Zerres K, Waeber G, Wareham N, Maxwell P, McCarthy M, Jarvelin M, Mooser V, Abecasis G, Lightstone L, Scott J, Navis G, Elliott P, Kooner J.

   Nature 2011 DOI
4. Genome-Wide Association Study Identifies Loci Influencing Concentrations of Liver Enzymes in Plasma. Chambers J, Zhang W, Sehmi J, Li X, Wass M, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister S, Coin L, Deng G, Gieger C, Heard-Costa N, Hottenga J, Kühnel B, Kumar V, Lagou V, Liang L, Luan J, Vidal P, Mateo Leach I, O’Reilly P, Peden J, Rahmioglu N, Soininen P, Speliotes E, Yuan X, Thorleifsson G, Alizadeh B, Atwood L, Borecki I, Brown M, Charoen P, Cucca F, Das D, de Geus E, Dixon A, Döring A, Ehret G, Eyjolfsson G, Farrall M, Forouhi N, Friedrich N, Goessling W, Gudbjartsson D, Harris T, Hartikainen A, Heath S, Hirschfield G, Hofman A, Homuth G, Hyppönen E, Janssen H, Johnson T, Kangas A, Kema I, Kühn J, Lai S, Lathrop M, Lerch M, Li Y, Liang T, Lin J, Loos R, Martin N, Moffatt M, Montgomery G, Munroe P, Musunuru K, Nakamura Y, O’Donnell C, Olafsson I, Penninx B, Pouta A, Prins B, Prokopenko I, Puls R, Ruokonen A, Savolainen M, Schlessinger D, Schouten J, Seedorf U, Sen-Chowdhry S, Siminovitch K, Smit J, Spector T, Tan W, Teslovich T, Tukiainen T, Uitterlinden A, Van der Klauw M, Vasan R, Wallace C, Wallaschofski H, Wichmann H, Willemsen G, Würtz P, Xu C, Yerges-Armstrong L, Alcohol Genome-wide Association (AlcGen) Consortium , Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study , Genetic Investigation of Anthropometric Traits (G. I. A. N. T) Consortium , Global Lipids Genetics Consortium and , Genetics of Liver Disease (G. O. L. D) Consortium , International Consortium for Blood Pressure (I. C. B. P-G. W. A. S) , Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) , Abecasis G, Ahmadi K, Boomsma D, Caulfield M, Cookson W, van Duijn C, Froguel P, Matsuda K, McCarthy M, Meisinger C, Mooser V, Pietiläinen K, Schumann G, Snieder H, Sternberg M, Stolk R, Thomas H, Thorsteinsdottir U, Uda M, Waeber G, Wareham N, Waterworth D, Watkins H, Whitfield J, Witteman J, Wolffenbuttel B, Fox C, Ala-Korpela M, Stefansson K, Vollenweider P, Völzke H, Schadt E, Scott J, Järvelin M, Elliott P, Kooner J.

   Nat Genet 2011 DOI
5. Genetic Association Analyses of Atopic Illness and Proinflammatory Cytokine Genes with Type 1 Diabetes. Saleh N, Raj S, Smyth D, Wallace C, Howson J, Bell L, Walker N, Stevens H, Todd J.

   Diabetes Metab Res Rev 2011 DOI
6. An Allele of IKZF1 (Ikaros) Conferring Susceptibility to Childhood Acute Lymphoblastic Leukemia Protects against Type 1 Diabetes. Swafford A, Howson J, Davison L, Wallace C, Smyth D, Schuilenburg H, Maisuria-Armer M, Mistry T, Lenardo M, Todd J.

   Diabetes 2011 DOI PMC
7. An Allele of IKZF1 (Ikaros) Conferring Susceptibility to Childhood Acute Lymphoblastic Leukemia Protects Against Type 1 Diabetes Swafford A, Howson J, Davison L, Wallace C, Smyth D, Schuilenburg H, Maisuria-Armer M, Mistry T, Lenardo M, Todd J.

   Diabetes 2011 DOI PMC
8. Dense Genotyping Identifies and Localizes Multiple Common and Rare Variant Association Signals in Celiac Disease. Trynka G, Hunt K, Bockett N, Romanos J, Mistry V, Szperl A, Bakker S, Bardella M, Bhaw-Rosun L, Castillejo G, de la Concha E, de Almeida R, Dias K, van Diemen C, Dubois P, Duerr R, Edkins S, Franke L, Fransen K, Gutierrez J, Heap G, Hrdlickova B, Hunt S, Izurieta L, Izzo V, Joosten L, Langford C, Mazzilli M, Mein C, Midah V, Mitrovic M, Mora B, Morelli M, Nutland S, NÃ\textordmasculineÃ\pmez C, Onengut-Gumuscu S, Pearce K, Platteel M, Polanco I, Potter S, Ribes-Koninckx C, RicaÃ\pmo-Ponce I, Rich S, Rybak A, Santiago J, Senapati S, Sood A, Szajewska H, Troncone R, VaradÃ\textcopyright J, Wallace C, Wolters V, Zhernakova A, Spanish Consortium on the Genetics of Coeliac Disease (C. E. G. E. C) , Prevent C. D Study Group , Wellcome Trust Case Control Consortium (W. T. C. C. C) , Thelma B, Cukrowska B, Urcelay E, Bilbao J, Mearin M, Barisani D, Barrett J, Plagnol V, Deloukas P, Wijmenga C, van Heel D.

   Nat Genet 2011 DOI
9. Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases. Plagnol V, Howson J, Smyth D, Walker N, Hafler J, Wallace C, Stevens H, Jackson L, Simmonds M, 1 Diabetes Genetics Consortium T, Bingley P, Gough S, Todd J.

   PLoS Genet 2011 DOI PMC
10. Pervasive Sharing of Genetic Effects in Autoimmune Disease Cotsapas C, Voight B, Rossin E, Lage K, Neale B, Wallace C, Abecasis G, Barrett J, Behrens T, Cho J, Jager P, Elder J, Graham R, Gregersen P, Klareskog L, Siminovitch K, van Heel D, Wijmenga C, Worthington J, Todd J, Hafler D, Rich S, Daly M, of Consortia F.

    PLoS Genet. 2011 DOI PMC

2010

1. Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes. Downes K, Pekalski M, Angus K, Hardy M, Nutland S, Smyth D, Walker N, Wallace C, Todd J.

   PLoS One 2010 DOI PMC
2. Genetic Loci Influencing Kidney Function and Chronic Kidney Disease. Chambers J, Zhang W, Lord G, van der Harst P, Lawlor D, Sehmi J, Gale D, Wass M, Ahmadi K, Bakker S, Beckmann J, Bilo H, Bochud M, Brown M, Caulfield M, Connell J, Cook H, Cotlarciuc I, Davey Smith G, de Silva R, Deng G, Devuyst O, Dikkeschei L, Dimkovic N, Dockrell M, Dominiczak A, Ebrahim S, Eggermann T, Farrall M, Ferrucci L, Floege J, Forouhi N, Gansevoort R, Han X, Hedblad B, Homan van der Heide J, Hepkema B, Hernandez-Fuentes M, Hypponen E, Johnson T, de Jong P, Kleefstra N, Lagou V, Lapsley M, Li Y, Loos R, Luan J, Luttropp K, Maréchal C, Melander O, Munroe P, Nordfors L, Parsa A, Peltonen L, Penninx B, Perucha E, Pouta A, Prokopenko I, Roderick P, Ruokonen A, Samani N, Sanna S, Schalling M, Schlessinger D, Schlieper G, Seelen M, Shuldiner A, Sjögren M, Smit J, Snieder H, Soranzo N, Spector T, Stenvinkel P, Sternberg M, Swaminathan R, Tanaka T, Ubink-Veltmaat L, Uda M, Vollenweider P, Wallace C, Waterworth D, Zerres K, Waeber G, Wareham N, Maxwell P, McCarthy M, Jarvelin M, Mooser V, Abecasis G, Lightstone L, Scott J, Navis G, Elliott P, Kooner J.

   Nat Genet 2010 DOI
3. Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes Downes K, Pekalski M, Angus K, Hardy M, Nutland S, Smyth D, Walker N, Wallace C, Todd J.

   PLoS One 2010 DOI PMC
4. Genome-Wide Association Study of CNVs in 16,000 Cases of Eight Common Diseases and 3,000 Shared Controls. Wellcome Trust Case Control Consortium , Craddock N, Hurles M, Cardin N, Pearson R, Plagnol V, Robson S, Vukcevic D, Barnes C, Conrad D, Giannoulatou E, Holmes C, Marchini J, Stirrups K, Tobin M, Wain L, Yau C, Aerts J, Ahmad T, Andrews T, Arbury H, Attwood A, Auton A, Ball S, Balmforth A, Barrett J, Barroso I, Barton A, Bennett A, Bhaskar S, Blaszczyk K, Bowes J, Brand O, Braund P, Bredin F, Breen G, Brown M, Bruce I, Bull J, Burren O, Burton J, Byrnes J, Caesar S, Clee C, Coffey A, Connell J, Cooper J, Dominiczak A, Downes K, Drummond H, Dudakia D, Dunham A, Ebbs B, Eccles D, Edkins S, Edwards C, Elliot A, Emery P, Evans D, Evans G, Eyre S, Farmer A, Ferrier I, Feuk L, Fitzgerald T, Flynn E, Forbes A, Forty L, Franklyn J, Freathy R, Gibbs P, Gilbert P, Gokumen O, Gordon-Smith K, Gray E, Green E, Groves C, Grozeva D, Gwilliam R, Hall A, Hammond N, Hardy M, Harrison P, Hassanali N, Hebaishi H, Hines S, Hinks A, Hitman G, Hocking L, Howard E, Howard P, Howson J, Hughes D, Hunt S, Isaacs J, Jain M, Jewell D, Johnson T, Jolley J, Jones I, Jones L, Kirov G, Langford C, Lango-Allen H, Lathrop G, Lee J, Lee K, Lees C, Lewis K, Lindgren C, Maisuria-Armer M, Maller J, Mansfield J, Martin P, Massey D, McArdle W, McGuffin P, McLay K, Mentzer A, Mimmack M, Morgan A, Morris A, Mowat C, Myers S, Newman W, Nimmo E, O’Donovan M, Onipinla A, Onyiah I, Ovington N, Owen M, Palin K, Parnell K, Pernet D, Perry J, Phillips A, Pinto D, Prescott N, Prokopenko I, Quail M, Rafelt S, Rayner N, Redon R, Reid D, Renwick , Ring S, Robertson N, Russell E, Clair D, Sambrook J, Sanderson J, Schuilenburg H, Scott C, Scott R, Seal S, Shaw-Hawkins S, Shields B, Simmonds M, Smyth D, Somaskantharajah E, Spanova K, Steer S, Stephens J, Stevens H, Stone M, Su Z, Symmons D, Thompson J, Thomson W, Travers M, Turnbull C, Valsesia A, Walker M, Walker N, Wallace C, Warren-Perry M, Watkins N, Webster J, Weedon M, Wilson A, Woodburn M, Wordsworth B, Young A, Zeggini E, Carter N, Frayling T, Lee C, McVean G, Munroe P, Palotie A, Sawcer S, Scherer S, Strachan D, Tyler-Smith C, Brown M, Burton P, Caulfield M, Compston A, Farrall M, Gough S, Hall A, Hattersley A, Hill A, Mathew C, Pembrey M, Satsangi J, Stratton M, Worthington J, Deloukas P, Duncanson A, Kwiatkowski D, McCarthy M, Ouwehand W, Parkes M, Rahman N, Todd J, Samani N, Donnelly P.

   Nature 2010 DOI PMC
5. The Imprinted DLK1-MEG3 Gene Region on Chromosome 14q32.2 Alters Susceptibility to Type 1 Diabetes. Wallace C, Smyth D, Maisuria-Armer M, Walker N, Todd J, Clayton D.

   Nat Genet 2010 DOI PMC
6. A Trans-Acting Locus Regulates an Anti-Viral Expression Network and Type 1 Diabetes Risk. Heinig M , Petretto E, Wallace C, Bottolo L, Rotival M, Lu H, Li Y, Sarwar R, Langley S, Bauerfeind A, Hummel O, Lee Y, Paskas S, Rintisch C, Saar K, Cooper J, Buchan R, Gray E, Cyster J, Consortium C, Erdmann J, Hengstenberg C, Maouche S, Ouwehand W, Rice C, Samani N, Schunkert H, Goodall A, Schulz H, Roider H, Vingron M, Blankenberg S, Maenzel T, Zeller T, Szymczak S, Ziegler A, Tiret L, Smyth D, Pravenec M, Aitman T, Cambien F, Clayton D, Todd J, Hubner N, Cook S.

   Nature 2010 DOI PMC

2009

1. Six New Loci Associated with Body Mass Index Highlight a Neuronal Influence on Body Weight Regulation. Willer C, Speliotes E, Loos R, Li S, Lindgren C, Heid I, Berndt S, Elliott A, Jackson A, Lamina C, Lettre G, Lim N, Lyon H, McCarroll S, Papadakis K, Qi L, Randall J, Roccasecca R, Sanna S, Scheet P, Weedon M, Wheeler E, Zhao J, Jacobs L, Prokopenko I, Soranzo N, Tanaka T, Timpson N, Almgren P, Bennett A, Bergman R, Bingham S, Bonnycastle L, Brown M, Burtt N, Chines P, Coin L, Collins F, Connell J, Cooper C, Smith G, Dennison E, Deodhar P, Elliott P, Erdos M, Estrada K, Evans D, Gianniny L, Gieger C, Gillson C, Guiducci C, Hackett R, Hadley D, Hall A, Havulinna A, Hebebrand J, Hofman A, Isomaa B, Jacobs K, Johnson T, Jousilahti P, Jovanovic Z, Khaw K, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta E, Luan J, Luben R, Mangino M, McArdle W, Meitinger T, Mulas A, Munroe P, Narisu N, Ness A, Northstone K, O’Rahilly S, Purmann C, Rees M, Ridderstrale M, Ring S, Rivadeneira F, Ruokonen A, Sandhu M, Saramies J, Scott L, Scuteri A, Silander K, Sims M, Song K, Stephens J, Stevens S, Stringham H, Tung Y, Valle T, Duijn C, Vimaleswaran K, Vollenweider P, Waeber G, Wallace C, Watanabe R, Waterworth D, Watkins N, Wellcome Trust Case Control Consortium , Witteman J, Zeggini E, Zhai G, Zillikens M, Altshuler D, Caulfield M, Chanock S, Farooqi I, Ferrucci L, Guralnik J, Hattersley A, Hu F, Jarvelin M, Laakso M, Mooser V, Ong K, Ouwehand W, Salomaa V, Samani N, Spector T, Tuomi T, Tuomilehto J, Uda M, Uitterlinden A, Wareham N, Deloukas P, Frayling T, Groop L, Hayes R, Hunter D, Mohlke K, Peltonen L, Schlessinger D, Strachan D, Wichmann H, McCarthy M, Boehnke M, Barroso I, Abecasis G, Hirschhorn J, Genetic Investigation of Anthropometric Traits Consortium .

   Nat Genet 2009
2. Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations Kolz M, Johnson T, Sanna S, Teumer A, Vitart V, Perola M, Mangino M, Albrecht E, Wallace C, Farrall M, Johansson A, Nyholt D, Aulchenko Y, Beckmann J, Bergmann S, Bochud M, Brown M, Campbell H, Connell J, Dominiczak A, Homuth G, Lamina C, McCarthy M, Meitinger T, Mooser V, Munroe P, Nauck M, Peden J, Prokisch H, Salo P, Salomaa V, Samani N, Schlessinger D, Uda M, Valker U, Waeber G, Waterworth D, Wang-Sattler R, Wright A, Adamski J, Whitfield J, Gyllensten U, Wilson J, Rudan I, Pramstaller P, Watkins H, Doering A, Wichmann H, Spector T, Peltonen L, Valzke H, Nagaraja R, Vollenweider P, Caulfield M, Illig T, Gieger C, for the EUROSPAN Consortium , for the ENGAGE Consortium , for the PROCARDIS Consortium , for the KORA Study , for the WTCCC .

   PLoS Genet 2009 DOI
3. Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution. Lindgren C, Heid I, Randall J, Lamina C, Steinthorsdottir V, Qi L, Speliotes E, Thorleifsson G, Willer C, Herrera B, Jackson A, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko Y, Chambers J, Drong A, Luan J, Lyon H, Rivadeneira F, Sanna S, Timpson N, Zillikens M, Zhao J, Almgren P, Bandinelli S, Bennett A, Bergman R, Bonnycastle L, Bumpstead S, Chanock S, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Doney A, Ebrahim S, Elliott P, Erdos M, Estrada K, Ferrucci L, Fischer G, Forouhi N, Gieger C, Grallert H, Groves C, Grundy S, Guiducci C, Hadley D, Hamsten A, Havulinna A, Hofman A, Holle R, Holloway J, Illig T, Isomaa B, Jacobs L, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Lathrop G, Lawlor D, Mangino M, McArdle W, Meitinger T, Morken M, Morris A, Munroe P, Narisu N, NordstrÃm A, NordstrÃm P, Oostra B, Palmer C, Payne F, Peden J, Prokopenko I, RenstrÃm F, Ruokonen A, Salomaa V, Sandhu M, Scott L, Scuteri A, Silander K, Song K, Yuan X, Stringham H, Swift A, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Walters G, Weedon M, WTCCC , Witteman J, Zhang C, Zhang W, Caulfield M, Collins F, Smith G, Day I, Franks P, Hattersley A, Hu F, Jarvelin M, Kong A, Kooner J, Laakso M, Lakatta E, Mooser V, Morris A, Peltonen L, Samani N, Spector T, Strachan D, Tanaka T, Tuomilehto J, Uitterlinden A, van Duijn C, Wareham N, Watkins H, Procardis Consortia , Waterworth D, Boehnke M, Deloukas P, Groop L, Hunter D, Thorsteinsdottir U, Schlessinger D, Wichmann H, Frayling T, Abecasis G, Hirschhorn J, Loos R, Stefansson K, Mohlke K, Barroso I, McCarthy M, Giant Consortium .

   PLoS Genet 2009 DOI
4. Polymorphisms in the WNK1 Gene Are Associated with Blood Pressure Variation and Urinary Potassium Excretion. Newhouse S, Farrall M, Wallace C, Hoti M, Burke B, Howard P, Onipinla A, Lee K, Shaw-Hawkins S, Dobson R, Brown M, Samani N, Dominiczak A, Connell J, Lathrop G, Kooner J, Chambers J, Elliott P, Clarke R, Collins R, Laan M, Org E, Juhanson P, Veldre G, Viigimaa M, Eyheramendy S, Cappuccio F, Ji C, Iacone R, Strazzullo P, Kumari M, Marmot M, Brunner E, Caulfield M, Munroe P.

   PLoS ONE 2009 DOI
5. Common Genetic Variation near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies. Nolte I, Wallace C, Newhouse S, Waggott D, Fu J, Soranzo N, Gwilliam R, Deloukas P, Savelieva I, Zheng D, Dalageorgou C, Farrall M, Samani N, Connell J, Brown M, Dominiczak A, Lathrop M, Zeggini E, Wain L, WTCCC , DCCT/EDIC Research Group , Newton-Cheh C, Eijgelsheim M, Rice K, de Bakker P, QTGEN consortium , Pfeufer A, Sanna S, Arking D, QTSCD consortium , Asselbergs F, Spector T, Carter N, Jeffery S, Tobin M, Caulfield M, Snieder H, Paterson A, Munroe P, Jamshidi Y.

   PLoS One 2009 DOI
6. Genome-Wide Association Study Identifies Eight Loci Associated with Blood Pressure. Newton-Cheh C, Johnson T, Gateva V, Tobin M, Bochud M, Coin L, Najjar S, Zhao J, Heath S, Eyheramendy S, Papadakis K, Voight B, Scott L, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers J, Khaw K, Nilsson P, van der Harst P, Polidoro S, Grobbee D, Onland-Moret N, Bots M, Wain L, Elliott K, Teumer A, Luan J, Lucas G, Kuusisto J, Burton P, Hadley D, McArdle W, Wellcome Trust Case Control Consortium , Brown M, Dominiczak A, Newhouse S, Samani N, Webster J, Zeggini E, Beckmann J, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G, Waterworth D, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I, Sandhu M, Luben R, Crawford G, Jousilahti P, Perola M, Boehnke M, Bonnycastle L, Collins F, Jackson A, Mohlke K, Stringham H, Valle T, Willer C, Bergman R, Morken M, Döring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A, Wichmann H, Kathiresan S, Marrugat J, O’Donnell C, Schwartz S, Siscovick D, Subirana I, Freimer N, Hartikainen A, McCarthy M, O’Reilly P, Peltonen L, Pouta A, de Jong P, Snieder H, van Gilst W, Clarke R, Goel A, Hamsten A, Peden J, Seedorf U, Syvänen A, Tognoni G, Lakatta E, Sanna S, Scheet P, Schlessinger D, Scuteri A, Dörr M, Ernst F, Felix S, Homuth G, Lorbeer R, Reffelmann T, Rettig R, Völker U, Galan P, Gut I, Hercberg S, Lathrop G, Zelenika D, Deloukas P, Soranzo N, Williams F, Zhai G, Salomaa V, Laakso M, Elosua R, Forouhi N, Völzke H, Uiterwaal C, van der Schouw Y, Numans M, Matullo G, Navis G, Berglund G, Bingham S, Kooner J, Connell J, Bandinelli S, Ferrucci L, Watkins H, Spector T, Tuomilehto J, Altshuler D, Strachan D, Laan M, Meneton P, Wareham N, Uda M, Jarvelin M, Mooser V, Melander O, Loos R, Elliott P, Abecasis G, Caulfield M, Munroe P.

   Nat Genet 2009 DOI PMC

2008

1. Genome-Wide Association Study Identifies Novel Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia Wallace C, Newhouse S, Braund P, Zhang F, Tobin M, Falchi M, Ahmadi K, Dobson R, Marçano A, Hajat C, Burton P, Deloukas P, Brown M, Connell J, Dominiczak A, Lathrop G, Webster J, The Wellcome Trust Case Control Consortium , Farrall M, Spector T, Samani N, Caulfield M, Munroe P.

   Am J Hum Genet 2008 DOI
2. Glutathione S-Transferase Variants and Hypertension. Delles C, Padmanabhan S, Lee W, Miller W, McBride M, McClure J, Brain N, Wallace C, MarÃ\textsectionano A, Schmieder R, Brown M, Caulfield M, Munroe P, Farrall M, Webster J, Connell J, Dominiczak A.

   J Hypertens 2008 DOI
3. Genome-Wide Association Analysis Identifies 20 Loci That Influence Adult Height. Weedon M, Lango H, Lindgren C, Wallace C, Evans D, Mangino M, Freathy R, Perry J, Stevens S, AS H, Samani N, Shields B, Prokopenko I, Farrall M, Dominiczak A, Diabetes Genetics Initiative , Wellcome Trust Case Control Consortium , Johnson T, Bergmann S, Beckmann J, Vollenweider P, Waterworth D, Mooser V, Palmer C, Morris A, Ouwehand W, Cambridge GEM Consortium , Zhao J, Li S, Loos R, Barroso I, Deloukas P, Sandhu M, Wheeler E, Soranzo N, Inouye M, Wareham N, Caulfield M, Munroe P, Hattersley A, McCarthy M, Frayling T.

   Nat Genet 2008 DOI
4. SLC2A9 Is a High-Capacity Urate Transporter in Humans. Caulfield M, Munroe P, O’Neill D, Witkowska K, Charchar F, Doblado M, Evans S, Eyheramendy S, Onipinla A, Howard P, Shaw-Hawkins S, Dobson R, Wallace C, Newhouse S, Brown M, Connell J, Dominiczak A, Farrall M, Lathrop G, Samani N, Kumari M, Marmot M, Brunner E, Chambers J, Elliott P, Kooner J, Laan M, Org E, Veldre G, Viigimaa M, Cappuccio F, Ji C, Iacone R, Strazzullo P, Moley K, Cheeseman C.

   PLoS Med 2008 DOI
5. Extreme Clonality in Lymphoblastoid Cell Lines with Implications for Allele Specific Expression Analyses Plagnol, Vincent AND Uz, Elif AND C Wallace AND Stevens, Helen AND Clayton, David AND Ozcelik, Tayfun AND Todd, John A. .

   PLoS ONE 2008 DOI PMC
6. Common Variants near MC4R Are Associated with Fat Mass, Weight and Risk of Obesity Loos R, Lindgren C, Li S, Wheeler E, Zhao J, Prokopenko I, Inouye M, Freathy R, Attwood A, Beckmann J, Berndt S, Prostate , Trial O, Jacobs K, Chanock S, Hayes R, Bergmann S, Bennett A, Bingham S, Bochud M, Brown M, Cauchi S, Connell J, Cooper C, Smith G, Day I, Dina C, De S, Dermitzakis E, Doney A, Elliott K, Elliott P, Evans D, Farooqi I, Froguel P, Ghori J, Groves C, Gwilliam R, Hadley D, Hall A, Hattersley A, Hebebrand J, Heid I, A. K, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann H, Herrera B, Hinney A, Hunt S, Jarvelin M, Johnson T, Jolley J, Karpe F, Keniry A, Khaw K, Luben R, Mangino M, Marchini J, McArdle W, McGinnis R, Meyre D, Munroe P, Morris A, Ness A, Neville M, Nica A, Ong K, O’Rahilly S, Owen K, Palmer C, Papadakis K, Potter S, Pouta A, Qi L, Study N, Randall J, Rayner N, Ring S, Sandhu M, Scherag A, Sims M, Song K, Soranzo N, Speliotes E, Initiative D, Syddall H, Teichmann S, Timpson N, Tobias J, Uda M, Study S, Vogel C, Wallace C, Waterworth D, Weedon M, Consortium W, Willer C, N. F, Wraight , Yuan X, Zeggini E, Hirschhorn J, Strachan D, Ouwehand W, Caulfield M, Samani N, Frayling T, Vollenweider P, Waeber G, Mooser V, Deloukas P, McCarthy M, Wareham N, Barroso I, Jacobs K, Chanock S, Hayes R, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann H, Kraft P, Hankinson S, Hunter D, Hu F, Lyon H, Voight B, Ridderstrale M, Groop L, Scheet P, Sanna S, Abecasis G, Albai G, Nagaraja R, Schlessinger D, Jackson A, Tuomilehto J, Collins F, Boehnke M, Mohlke K.

   Nat. Genet. 2008 DOI PMC

2007

1. Information Capture Using SNPs from HapMap and Whole-Genome Chips Differs in a Sample of Inflammatory and Cardiovascular Gene-Centric Regions from Genome-Wide Estimates. Wallace C, Dobson R, Munroe P, Caulfield M.

   Genome Res 2007 DOI
2. Genetic Association Analysis of Inositol Polyphosphate Phosphatase-like 1 (INPPL1, SHIP2) Variants with Essential Hypertension. Marçano A, Burke B, Gungadoo J, Wallace C, Kaisaki P, Woon P, Farrall M, Clayton D, Brown M, Dominiczak A, Connell J, Webster J, Lathrop M, Caulfield M, Samani N, Gauguier D, Munroe P.

   J Med Genet 2007 DOI
3. Genome-Wide Association Study of 14,000 Cases of Seven Common Diseases and 3,000 Shared Controls Burton P, Clayton D, Cardon L, Craddock N, Deloukas P, Duncanson A, Kwiatkowski D, McCarthy M, Ouwehand W, Samani N, Todd J, Donnelly P, Barrett J, Burton P, Davison D, Donnelly P, Easton D, Evans D, Leung H, Marchini J, Morris A, Spencer C, Tobin M, Cardon L, Clayton D, Attwood A, Boorman J, Cant B, Everson U, Hussey J, Jolley J, Knight A, Koch K, Meech E, Nutland S, Prowse C, Stevens H, Taylor N, Walters G, Walker N, Watkins N, Winzer T, Todd J, Ouwehand W, Jones R, McArdle W, Ring S, Strachan D, Pembrey M, Breen G, St Clair D, Caesar S, Gordon-Smith K, Jones L, Fraser C, Green E, Grozeva D, Hamshere M, Holmans P, Jones I, Kirov G, Moskvina V, Nikolov I, O’Donovan M, Owen M, Craddock N, Collier D, Elkin A, Farmer A, Williamson R, McGuffin P, Young A, Ferrier I, Ball S, Balmforth A, Barrett J, Bishop D, Iles M, Maqbool A, Yuldasheva N, Hall A, Braund P, Burton P, Dixon R, Mangino M, Stevens S, Tobin M, Thompson J, Samani N, Bredin F, Tremelling M, Parkes M, Drummond H, Lees C, Nimmo E, Satsangi J, Fisher S, Forbes A, Lewis C, Onnie C, Prescott N, Sanderson J, Mathew C, Barbour J, Mohiuddin M, Todhunter C, Mansfield J, Ahmad T, Cummings F, Jewell D, Webster J, Brown M, Clayton D, Lathrop G, Connell J, Dominiczak A, Samani N, Marcano C, Burke B, Dobson R, Gungadoo J, Lee K, Munroe P, Newhouse S, Onipinla A, Wallace C, Xue M, Caulfield M, Farrall M, Barton A, Genomics (BRAGGS) T, Bruce I, Donovan H, Eyre S, Gilbert P, Hider S, Hinks A, John S, Potter C, Silman A, Symmons D, Thomson W, Worthington J, Clayton D, Dunger D, Nutland S, Stevens H, Walker N, Widmer B, Todd J, Frayling T, Freathy R, Lango H, Perry J, Shields B, Weedon M, Hattersley A, Hitman G, Walker M, Elliott K, Groves C, Lindgren C, Rayner N, Timpson N, Zeggini E, McCarthy M, Newport M, Sirugo G, Lyons E, Vannberg F, Hill A, Bradbury L, Farrar C, Pointon J, Wordsworth P, Brown M, Franklyn J, Heward J, Simmonds M, Gough S, Seal S, Susceptibility Collaboration (UK) B, Stratton M, Rahman N, Ban M, Goris A, Sawcer S, Compston A, Conway D, Jallow M, Newport M, Sirugo G, Rockett K, Kwiatkowski D, Bumpstead S, Chaney A, Downes K, Ghori M, Gwilliam R, Hunt S, Inouye M, Keniry A, King E, McGinnis R, Potter S, Ravindrarajah R, Whittaker P, Widden C, Withers D, Deloukas P, Leung H, Nutland S, Stevens H, Walker N, Todd J, Easton D, Clayton D, Burton P, Tobin M, Barrett J, Evans D, Morris A, Cardon L, Cardin N, Davison D, Ferreira T, Pereira-Gale J, Hallgrimsdóttir I, Howie B, Marchini J, Spencer C, Su Z, Teo Y, Vukcevic D, Donnelly P, Bentley D, Brown M, Cardon L, Caulfield M, Clayton D, Compston A, Craddock N, Deloukas P, Donnelly P, Farrall M, Gough S, Hall A, Hattersley A, Hill A, Kwiatkowski D, Mathew C, McCarthy M, Ouwehand W, Parkes M, Pembrey M, Rahman N, Samani N, Stratton M, Todd J, Worthington J.

   Nature 2007 DOI
4. Association Scan of 14,500 Nonsynonymous SNPs in Four Diseases Identifies Autoimmunity Variants Wellcome Trust Case Control Consortium , Australo-Anglo-American Spondylitis Consortium (TASC) , Burton P, Clayton D, Cardon L, Craddock N, Deloukas P, Duncanson A, Kwiatkowski D, McCarthy M, Ouwehand W, Samani N, Todd J, Donnelly P, Barrett J, Davison D, Easton D, Evans D, Leung H, Marchini J, Morris A, Spencer C, Tobin M, Attwood A, Boorman J, Cant B, Everson U, Hussey J, Jolley J, Knight A, Koch K, Meech E, Nutland S, Prowse C, Stevens H, Taylor N, Walters G, Walker N, Watkins N, Winzer T, Jones R, McArdle W, Ring S, Strachan D, Pembrey M, Breen G, St Clair D, Caesar S, Gordon-Smith K, Jones L, Fraser C, Green E, Grozeva D, Hamshere M, Holmans P, Jones I, Kirov G, Moskivina V, Nikolov I, O’Donovan M, Owen M, Collier D, Elkin A, Farmer A, Williamson R, McGuffin P, Young A, Ferrier I, Ball S, Balmforth A, Barrett J, Bishop T, Iles M, Maqbool A, Yuldasheva N, Hall A, Braund P, Dixon R, Mangino M, Stevens S, Thompson J, Bredin F, Tremelling M, Parkes M, Drummond H, Lees C, Nimmo E, Satsangi J, Fisher S, Forbes A, Lewis C, Onnie C, Prescott N, Sanderson J, Matthew C, Barbour J, Mohiuddin M, Todhunter C, Mansfield J, Ahmad T, Cummings F, Jewell D, Webster J, Brown M, Lathrop M, Connell J, Dominiczak A, Marcano C, Burke B, Dobson R, Gungadoo J, Lee K, Munroe P, Newhouse S, Onipinla A, Wallace C, Xue M, Caulfield M, Farrall M, Barton A, Biologics in RA Genetics and Genomics Study Syndicate (BRAGGS) Steering Committee , Bruce I, Donovan H, Eyre S, Gilbert P, Hilder S, Hinks A, John S, Potter C, Silman A, Symmons D, Thomson W, Worthington J, Dunger D, Widmer B, Frayling T, Freathy R, Lango H, Perry J, Shields B, Weedon M, Hattersley A, Hitman G, Walker M, Elliott K, Groves C, Lindgren C, Rayner N, Timpson N, Zeggini E, Newport M, Sirugo G, Lyons E, Vannberg F, Hill A, Bradbury L, Farrar C, Pointon J, Wordsworth P, Brown M, Franklyn J, Heward J, Simmonds M, Gough S, Seal S, Breast Cancer Susceptibility Collaboration (UK) , Stratton M, Rahman N, Ban M, Goris A, Sawcer S, Compston A, Conway D, Jallow M, Newport M, Sirugo G, Rockett K, Bumpstead S, Chaney A, Downes K, Ghori M, Gwilliam R, Hunt S, Inouye M, Keniry A, King E, McGinnis R, Potter S, Ravindrarajah R, Whittaker P, Widden C, Withers D, Cardin N, Davison D, Ferreira T, Pereira-Gale J, Hallgrimsdo’ttir I, Howie B, Su Z, Teo Y, Vukcevic D, Bentley D, Brown M, Compston A, Farrall M, Hall A, Hattersley A, Hill A, Parkes M, Pembrey M, Stratton M, Mitchell S, Newby P, Brand O, Carr-Smith J, Pearce S, McGinnis R, Keniry A, Deloukas P, Reveille J, Zhou X, Sims A, Dowling A, Taylor J, Doan T, Davis J, Savage L, Ward M, Learch T, Weisman M, Brown M.

   Nat. Genet. 2007 DOI PMC
5. Robust Associations of Four New Chromosome Regions from Genome-Wide Analyses of Type 1 Diabetes. Todd J, Walker N, Cooper J, Smyth D, Downes K, Plagnol V, Bailey R, Nejentsev S, Field S, Payne F, Lowe C, Szeszko J, Hafler J, Zeitels L, Yang J, Vella A, Nutland S, Stevens H, Schuilenburg H, Coleman G, Maisuria M, Meadows W, Smink L, Healy B, Burren O, Lam A, Ovington N, Allen J, Adlem E, Leung H, Wallace C, Howson J, Guja C, Ionescu-TÃ&#0174rgoviste C, of Type 1 Diabetes in Finland G, Simmonds M, Heward J, Gough S, Dunger D, Wellcome Trust Case Control Consortium , Wicker L, Clayton D.

   Nat Genet 2007 DOI PMC

2006

1. Appropriate Use of Information on Family History of Disease in Recruitment for Linkage Analysis Studies Wallace C, Clayton D.

   Ann Hum Genet 2006 DOI
2. Improved Power Offered by a Score Test for Linkage Disequilibrium Mapping of Quantitative-Trait Loci by Selective Genotyping. Wallace C, Chapman J, Clayton D.

   Am J Hum Genet 2006 DOI
3. Linkage Analysis Using Co-Phenotypes in the BRIGHT Study Reveals Novel Potential Susceptibility Loci for Hypertension Wallace C, Xue M, Newhouse S, Marçano A, Onipinla A, Burke B, Gungadoo J, Dobson R, Brown M, Connell J, Dominiczak A, Lathrop G, Webster J, Farrall M, Mein C, Samani N, Caulfield M, Clayton D, Munroe P.

   Am J Hum Genet 2006
4. Increased Support for Linkage of a Novel Locus on Chromosome 5q13 for Essential Hypertension in the British Genetics of Hypertension Study. Munroe P, Wallace C, Xue M, MarÃ\textsectionano A, Dobson R, Onipinla A, Burke B, Gungadoo J, Newhouse S, Pembroke J, Brown M, Dominiczak A, Samani N, Lathrop M, Connell J, Webster J, Clayton D, Farrall M, Mein C, Caulfield M, Medical Research Council British Genetics of Hypertension Study .

   Hypertension 2006
5. Two-Dimensional Genome Scan Identifies Novel Epistatic Loci for Essential Hypertension. Bell J, Wallace C, Dobson R, Wiltshire S, Mein C, Pembroke J, Brown M, Clayton D, Samani N, Dominiczak A, Webster J, Lathrop G, Connell J, Munroe P, Caulfield M, Farrall M.

   Hum Mol Genet 2006 DOI
6. Haplotypes of the Beta-2 Adrenergic Receptor Associate with High Diastolic Blood Pressure in the Caerphilly Prospective Study. Binder A, Garcia E, Wallace C, Gbenga K, Ben-Shlomo Y, Yarnell J, Brown P, Caulfield M, Skrabal F, Kotanko P, Munroe P.

   J Hypertens 2006 DOI
7. Chromosome 2p Shows Significant Linkage to Antihypertensive Response in the BRItish Genetics of HyperTension Study. Padmanabhan S, Wallace C, Munroe P, Dobson R, Brown M, Samani N, Clayton D, Farrall M, Webster J, Lathrop M, Caulfield M, Dominiczak A, Connell J.

   Hypertension 2006 DOI

2005

1. Haplotypes of the WNK1 Gene Associate with Blood Pressure Variation in a Severely Hypertensive Population from the British Genetics of Hypertension Study. Newhouse S, Wallace C, Dobson R, Mein C, Pembroke J, Farrall M, Clayton D, Brown M, Samani N, Dominiczak A, Connell J, Webster J, Lathrop G, Caulfield M, Munroe P.

   Hum Mol Genet 2005 DOI

2004

1. Linkage Analysis of Susceptibility to Leprosy Type Using an IBD Regression Method. Wallace C, Fitness J, Hennig B, Sichali L, Mwaungulu L, Pönnighaus J, Warndorff D, Clayton D, Fine P, Hill A.

   Genes Immun 2004 DOI

2003

1. Trends in Drug Overdose Deaths in England and Wales 1993-98: Methadone Does Not Kill More People than Heroin. Hickman M, Madden P, Henry J, Baker A, Wallace C, Wakefield J, Stimson G, Elliott P.

   Addiction 2003
2. Estimating the Relative Recurrence Risk Ratio Using a Global Cross-Ratio Model. Wallace C, Clayton D.

   Genet Epidemiol 2003 DOI
3. Estimating the Relative Recurrence Risk Ratio for Leprosy in Karonga District, Malawi. Wallace C, Clayton D, Fine P.

   Lepr Rev 2003

2001

1. Measuring Differences in the Provision of Diabetes Care New J, Roxburgh M, Vaughan N, Wallace C, Elliott P, Young R.

   Diabetes Nutrition & Metabolism 2001