simulate betas for a study simulate_study use the multivariate normal to simulate realistic betas for a study

simulate betas for a study simulate_study use the multivariate normal to simulate realistic betas for a study

simulate_study(DT, ref_gt_dir, shrink_beta = TRUE, n_sims = 10,
  quiet = TRUE)

Arguments

DT

a data.table - as returned by get_gwas_data
ref_gt_dir

scalar - path to a dir of R objects named CHR_1kg.RData containing reference GT in snpMatrix format
shrink_beta

scalar - Whether to use Bayesian shrinkage of betas (default = TRUE)
n_sims

a scalar - number of simulations (default 10)
quiet

a scalar - boolean whether to show progress messages

Value

a DT of n_sims simulated studies for projection