Internal helper function for est_all_cond
est_cond(x, LD, YY, sigsnps, xtx = NULL)
Arguments
- x
coloc dataset
- LD
named matrix of r
- YY
sum((Y-Ybar)^2)
- sigsnps
names of snps to jointly condition on
- xtx
optional, matrix X'X where X is the genotype matrix. If
not available, will be estimated from LD, MAF, beta and sample
size (the last three should be part of the coloc dataset)
Value
data.table giving snp, beta and varbeta on remaining snps
after conditioning