Coloc data structureDescription of coloc data structure |
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check_dataset |
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Bayesian enumeration of hypothesesTwo trait colocalisation and single trait fine mapping under single causal variant assumptions |
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Fully Bayesian colocalisation analysis using Bayes Factors |
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Bayesian finemapping analysis |
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Sensitivity analysisCheck how robust inference is to changing prior parameter values |
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Prior sensitivity for coloc |
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Relaxing the single variant assumptionuse conditioning or masking to account for multiple independent causal variants per trait |
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run coloc using susie to detect separate signals |
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Run susie on a single coloc-structured dataset |
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Othersincluded for completeness, but the main functions you need should be in the sections above |
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Var.data |
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Var.data |
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Internal function, approx.bf.estimates |
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Internal function, approx.bf.p |
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binomial to linear regression conversion |
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check alignment |
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Colocalisation tests of two genetic traits |
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Coloc data through Bayes factors |
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Bayesian colocalisation analysis with detailed output |
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Post process a coloc.details result using masking |
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Coloc with multiple signals per trait |
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run coloc using susie to detect separate signals |
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Simulated data to use in testing and vignettes in the coloc package |
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combine.abf |
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generate conditional summary stats |
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estgeno1 |
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Pick out snp with most extreme Z score |
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trim a dataset to central peak(s) |
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trim a dataset to only peak(s) |
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Finemap data through Bayes factors |
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Finemap multiple signals in a single dataset |
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logbf 2 pp |
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logdiff |
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logsum |
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find the next most significant SNP, conditioning on a list of sigsnps |
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find the next most significant SNP, masking a list of sigsnps |
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plot a coloc_abf object |
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plot a coloc dataset |
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print.coloc_abf |
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process.dataset |
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Estimate trait variance, internal function |
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subset_dataset |